PARTNER

Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients

In high-risk patients with severe aortic stenosis, transcatheter and surgical procedures for aortic-valve replacement were associated with similar rates of survival at 1 year, although there were important differences in periprocedural risks.

PARTNER 2

Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients

In intermediate-risk patients, TAVR was similar to surgical aortic-valve replacement with respect to the primary end point of death or disabling stroke.

PARTNER 3

Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

Among patients with severe aortic stenosis who were at low surgical risk, the rate of the composite of death, stroke, or rehospitalization at 1 year was significantly lower with TAVR than with surgery.

Core Valve

Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

In patients with severe aortic stenosis who are at increased surgical risk, TAVR with a self-expanding transcatheter aortic-valve bioprosthesis was associated with a significantly higher rate of survival at 1 year than surgical aortic-valve replacement.

SURTAVI

Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients

TAVR was a noninferior alternative to surgery in patients with severe aortic stenosis at intermediate surgical risk, with a different pattern of adverse events associated with each procedure.

POPULAR TAVI

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation