Chronic Inflammatory Diseases Vary Widely in CHD Risk
SLE: hazard ratio for CHD, 2.85; for MI, 4.76.
Systemic sclerosis: HR for CHD, 2.14; for MI, 3.19.
HIV: HR for CHD, 1.38; for MI, 1.69.
Rheumatoid arthritis: HR for CHD, 1.22; for MI, 1.45.
Psoriasis: no significant increase.
RHAPSODY Rilonacept (Interleukin-1 Trap) Resolves, Prevents Pericarditis Recurrence
Among patients with recurrent pericarditis, rilonacept led to rapid resolution of recurrent pericarditis episodes and to a significantly lower risk of pericarditis recurrence than placebo
Transseptal SAPIEN 3 MViV was associated with rare procedural complications and low mortality and should be considered an option for most patients with failed surgical bioprosthetic mitral valves.
Association Between Malignant Mitral Valve Prolapse and Sudden Cardiac Death
A Review
SCD can occur earlier in the course of MVP from complex arrhythmias that are triggered by the repeated tugging and traction of the chordopapillary muscle unit and basal mid-myocardium, even before macrofibrosis can be identified in these regions by late gadolinium enhancement on cardiac magnetic resonance imaging
Vericiguat
Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
VICTORIA
Among patients with high-risk heart failure, the incidence of death from cardiovascular causes or hospitalization for heart failure was lower among those who received vericiguat than among those who received placebo.
Omecamtiv Mecarbil
COSMIC-HF
Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial
GALACTIC-HF