ULCERATIVE COLITIS

Budesonide

CORE 1

Sulfasalazine

ASCEND 1,2,3

Azathioprine + Infliximab

UC  SUCCESS

Infliximab for refractory UC

ACT 1 & 2

Golimumab

PERSUITE

Infliximab & Cyclosporine superior than alone in Steroid resistant UC

CONSTRUCT

CROHNS DISEASE

Azathioprine + Infliximab better than Azathioprine

SONIC

Inflixiamab in fistula

ACCENT

Adalilumab

GAIN