ACCORD-BP
BP <140 vs <120
No benefit of MI,CVD
Stroke risk lower, but not sustained
ADVANCE-BP
Compared to 136 vs 142
Reduced micro & macro vascular complications
ADVANCE-ON
Intensive BP lowering benefit
HOT
DBP <80 better than <90 in DM
(others no benefit)
Intensive lowering of blood pressure in patients with hypertension was associated with a low rate of cardiovascular events.
SPRINT
SBP <120 was better than <140