ACCORD-BP

BP <140 vs <120

No benefit of MI,CVD

Stroke risk lower, but not sustained

ADVANCE-BP

Compared to 136 vs 142

Reduced micro & macro vascular complications

ADVANCE-ON

Intensive BP lowering benefit

HOT

DBP <80 better than <90 in DM

(others no benefit)

Intensive lowering of blood pressure in patients with hypertension was associated with a low rate of cardiovascular events.

SPRINT

SBP <120 was better than <140